HORI Ikuma

Researcher HORI IkumaSpecially-Appointed Asst. Prof.

HORI Ikuma
Specially-Appointed Asst. Prof.

Fields Neuroscience, Molecular Biology
Project
  • Ambitious Special Assistant Prof.
/
  • FY2025

Research Outline

Neurodegenerative diseases, such as dementia, Alzheimer’s disease, and stroke, become more prevalent with age, presenting significant challenges to quality of life. In today’s aging society, the number of patients with these conditions is expected to rise, making the development of early diagnosis techniques and novel therapies an urgent priority. Mitochondria, which are essential for maintaining normal neuronal function, are thought to decline in function with aging. They may also trigger inflammatory responses in the early stages of neurodegenerative diseases. Understanding changes in mitochondrial function may provide new insights for diagnosis and treatment. However, the extent to which mitochondria contribute to the pathogenesis of these diseases is still largely unknown. Therefore, we are currently investigating the possibility of new diagnostic techniques based on changes in mitochondrial function and attempting to search for factors that can serve as therapeutic targets. Through this research, we aim to enhance our understanding of the pathogenesis of neurodegenerative diseases and contribute to the development of effective diagnostic and therapeutic methods.